Folic Acid Treatment to Crohn's Disease

Folic Acid in Coeliac Disease

Folic acid, as a component of the vitamin B complex, has ben recognized for many years as an estial food factor. Crude preparations of it we shown to have a haernopoietic effect in some animals. Deficiency of it was followed by depression of the formation of red cells, white cells, and platelets. In 1945 Angier et aL (1945) synthesized pure folic acid. Spies (1945) and his co-workers were the f...

Folic Acid Supplementation: to Advise or not to Advise?

Pinworm Infestation Mimicking Crohns' Disease

We here report a case of a young man who presented to his general practitioner with diarrhea. Inflammatory bowel disease was suspected and a colonoscopy showed aphthous lesions suggestive of Crohns' disease but biopsies revealed eggs of Enterobius vermicularis. When treated for this parasite, his symptoms were alleviated and a followup colonoscopy revealed a normal colon and distal ileum. Enter...

Folic acid supplementation during methotrexate treatment: nonsense?

histological changes, and therefore this was not adequate to demonstrate response. Given her prolonged course and poor muscle mass at this stage, we expected subtle clinical changes with minimal initial improvement in muscle strength. Infusions (5mg/kg) were administered at weeks 0, 2, 6 and 14. She continued with prednisone and mycophenolate. A remarkable response was observed in muscle streng...

Folic acid fortification and congenital heart disease.

Background: Low plasma folate concentrations in pregnancy are associated with preterm birth. Here we show an association between preconceptional folate supplementation and the risk of spontaneous preterm birth. Methods and Findings: In a cohort of 34,480 low-risk singleton pregnancies enrolled in a study of aneuploidy risk, preconceptional folate supplementation was prospectively recorded in th...